Pharmachology

Pharmachology

cholinergic antagonist practice test [The beautiful thing about learning is that no one can take it away from you]

published on November 11, 2012
1/19

action of atropine?

Hint: 3 choices
low dose: CO decrease result in bradycardia b/c of blockage of M1 receptor
high dose: CO increase rsult in tachycardia b/c of blockage of M2 receptor
arterial BP is unaffected
all of the above are wrong
2/19

theraputic use of scopolamine?

Hint: 2 choices
prevent motion sickness
stimulate secretion
blocking short term memory
3/19

which of the followings are true about ganglionic blockers?

act on nicotonic receptors of both parasympathetic and sympathetic autonomic ganglia
some block ion channels of autonomic ganglia
block entire outcome of ANS at nicotinic receptor
ganglionic blockers are rarely used for therapeutic purpose
4/19

which is not true about atropine?

Hint: 1 choice
block secretions: causes xerostomia
stimulate secretion
adverse effects: dry mouth blurred vison tachy cardia constipation
5/19

which is true about trimethaphan?

Hint: 1 choice
used in emergency to decrease BP
used in emergency to increase BP
not helpful in BP
6/19

which of the followings are wrong about tropicamide and cyclopentolate?

actions used as opthalmic (mydriasis and cycloplegia)
duration shorter than atropine
actions used as opthalmic ( miosis)
7/19

anti muscranic agents?

Hint: 3 choices
block muscranic synapses of parasympathetic nerves
doesnt block symathetic nerves except those of sweat and salivary glands
have little or no action at skeletal neuromuscular juntion or autonomic ganglia
doesnt block muscranic synapses of parasympathetic nerves
8/19

which of the followings are not true about nicotine?

depolarize autonomic ganglia resulting first in stimulation and then paralysis of all ganglia
people use it for stoping cigratte smoking
increases,BP,cardiac rate, peristalsis,secretions
at higher does decrease BP GIT and bladder
at higher does it increases BP
9/19

which is not true about mecamylamine?

competitive nicotinic blockage of ganglia
oral administeration
all of the above are wrong
10/19

which drug helps in atropine toxicity?

Hint: 1 choice
physostigamine
bethanechol
pilocarpine
11/19

which of the following drugs are antimuscarinic agents?

Hint: 5 choices
scopolamine
tropicamide
mecamylamine
cyclopentolate
atropine
ipratropium
12/19

which is wrong about pharmacokinetics of atropine?

partially metabolized by liver
eliminated primarily in urine
partially metabolized by intestines
13/19

which of the followings are true about ipratropium?

useful in treatment of asthma who are unable to take adrenergic agonist
in COPD its inhaled
because of its '+' charges it can't enter systemic circulatin or CNS
14/19

which of the following is true about atropine?

Hint: 3 choices
in patients with narrow angle glaucoma
gastric motility is reduced but production of HCl is not affected that is y the drug is not effective in peptic ulcer
useful in gastriac ulcer
block cholinergic activity results in percistant mydriasis(dilation of eye), unresponsiveness to light and cycloplegia
15/19

which of the following drugs are ganglionic blockers?

Hint: 2 choices
mecamylamine
atropine
nicotine
16/19

which of the following agents cholinergic antagonists have?

antimuscarinic agents
ganglionic blockers
neuromuscular blockers
17/19

in older patients atropine?

induce mydriasis and cycloplegia
may induce urinery retention
children are sensitive to atropine
18/19

which of the followings are true of scopolamine?

most effective, anti motion sickness
unusual efect of blocking short term memory
higher does: produce sedation
produce euphoria and subject to abuse
19/19

therapeutic uses of atropine?

opthalmic: mydriasis and cycloplegia
antispasmodic: relax GIT
antidote for cholenergic agonist
antisecratory