Pharmacology (2)

Question 1

1/44

trihexayphenidyl?

Answer

less efficious than levodopa

Answer

more effictive in tremor

Answer

less effective in bradykinesia and rigidity

Question 2

2/44

which of the following drugs in BZ is used for hypnosis?

flurazepam,temazepam,triazolam

Answer

chloradiazepoxide and diazepam

Answer

diazepam and flurazepam

Question 3

3/44

which of the following drug is used to treat grand mal epilepsy,partial epilepsy,anti peripheral neuralgia,antiarrhythmia?

phenytoin

Answer

barbiturate

Answer

succineamide

Question 4

4/44

therapeutic uses of levodopa?

Hint: 2 choices

Answer

effective for parkinsonian disease and syndrome

Answer

combination with L-dopa and carbidopa

Answer

effective only for parkinsonian disease

Question 5

5/44

which of the following drug cause small reduction in REM sleep?

chloralhydrate

Answer

paraldehydrate

Answer

phenobarbital

Question 6

6/44

due to following shortcomings benzodiazepines replaces BARB except?

induction of seizures

Answer

a narrow therapeutic index

Answer

shortening REMS

Answer

hight potential for physical dependence

Question 7

7/44

carbidopa?

Hint: 4 choices

Answer

inhibitor of dopa decarboxylase

Answer

reduce peripheral conversion of L-dopa to dopamine

Answer

uses: combination with L-dopa

Answer

its not used alone

Answer

can use alone

Question 8

8/44

which of the following BARB are highly lipid soluble?

ultra short acting barbiturates

Answer

long acting

Answer

short acting

Question 9

9/44

benzodiazepine includes?

chlordiazepoxide and diazepam

Answer

thiopental and hlordiazepoxide

Answer

L-dopa and carbidopa

Question 10

10/44

which of the following is the first choice for epileticism in adult?

Answer

phenobarbital

Answer

oral diazepam

Answer

magnesium sulfate injection

Question 11

11/44

characteristics of sleep induced by barbiturates is?

Answer

to shorten SEMS

Answer

to prolong SEMS

Answer

to prolong REMS

Answer

to shorten REMS and SEMS

Question 12

12/44

which drug is used for absence epilepsy as a second choice?

sodium valporate

BZ

MgSO4

Answer

tremor,muscular rigdety,bradykinesia

Answer

therapy: restablish dopamine/ Ach balance,to increase function of
dopaminergic neurons in nuostratium,to decrease function of
cholinergic neurons

Answer

clinical effects: relieving symptoms, not stopping progress

Answer

clinical effects: stopping progress

Answer

seccineamide

Answer

doesnt cross BBB

Answer

well absorbed from small intestine and 90% decarboxylated in periphral
and results in peripheral side effect

Answer

induction of seizures and shortening REMS

Answer

Induction of seizures and a narrow therapeutic index

Answer

barbiturates

Answer

grand mal seizure

Answer

psychomotor seizure

Answer

localizied seizure

Answer

intravenous infusion of NaHCO3

Answer

respiratory stimulant

Answer

cardiovascular stimulant

Answer

phenobarbital

Answer

amobarbital

Answer

succineamide

Answer

Florazepam and temazepam

Answer

chlorazepam and diazepam

Answer

tachycardia,arrythmia

Answer

vivid dream,mental disturbance,GIT(nausea vomiting)

Answer

no vit B6 during therapy

Answer

vit B6 during therapy

Answer

flurazepame

Answer

short acting

Answer

ultra short acting

Answer

agitation and confusion

Answer

restlessness

Answer

hallucination

Answer

stimulating synthesis and release of dopamine from surviving dopamine
nerve terminals

Answer

more effective than anti cholinergic agents

Answer

not effective for tremors

Answer

more effective than L-dopa in parkinson's disorder

Answer

antianxiety

Answer

anticonvulsion

Answer

barbiturate

Answer

chlordiazepoxide

Answer

flurazepam

Answer

sedative dose

Answer

large dose

Answer

thiopental

Answer

pentobarbital

Answer

chloralhydrate

Answer

phenobarbital

Answer

antianxiety

Answer

anticonvulsion

Answer

do not use alone for early parkinson's disease

Answer

alone used for early parkinson's disease

Answer

various parkinson's diseases: in combination with L-dopa

Answer

anticonvulsion

Answer

antiepileptism

Answer

chlonazepam

Answer

flurazepam

Answer

chlonazepam

Answer

flurazepam

Answer

alone for mild patients: patients of discontinuation L-dopa due to
adverse effects

Answer

all parkinson's disorders: in combination with L-dopa

Answer

not alone for mild patients: patients of discontinuation L-dopa due to
adverse effects

Answer

Barbiturates

Answer

carbamizepam

Answer

chlonazepam

Answer

dopaminomimetic) metabolite precursor:levodopa

Answer

dopaminomimetic) decarboxylase inhibitor:carbidopa

Answer

dopaminomimetic) DA receptor agonist: bromocriptine

Answer

dopaminomimetic) MAO inhibitor: selegiline

Answer

dopaminomimetic) COMT inhibitor: tocapone

Answer

dopaminomimetic) drug releasing dopamine: amantadine

Answer

anticholinergic drug: trihexyphenidy

Question 13

13/44

which of the followings are true about parkinsonian disorders?

Hint: 3 choices

Question 14

14/44

which of the following drugs are used as first choice in children's and infants?

barbiturates

BZ

Question 15

15/44

which are true about pharmacokinetics of Leodopa?

Hint: 2 choices

cross BBB

Question 16

16/44

BARB are being replaced by bensodiazepines (BZ) for clinical use as sedative hypnotic agents b/c of the following short comings ?

a narrow therapeutic index, shortening REMS and hight potential for
physical dependence

Question 17

17/44

which of the following drugs are lipophilic and rapidly absorbed by oral administration?

BZ

MgSO4

Question 18

18/44

the clinical uses of phenytoin include all of the following except?

minor seizure

Question 19

19/44

A patient suffering from toxication due to overdosage of barbiturates should be adminstered?

Question 20

20/44

intravenous anesthesia which drug is used?

thiopeutal

Question 21

21/44

drugs used in simple partial and grand mal epilepsy?

BZ

phenytoin

barbiturates

Question 22

22/44

which of the following drug is benzodiazepine causes anti anxiety?

chloradiazepoxide and diazepam

Question 23

23/44

adverse effect of levodopa?

Hint: 3 choices

Question 24

24/44

which of the following drug in BZ is used for chronic epilepsy?

diazepam

chlonazepam

Question 25

25/44

which of following BARB are lowerly lipid soluble?

long acting

Question 26

26/44

adverse effects of amantadine?

Question 27

27/44

amantadine?

Hint: 3 choices

Question 28

28/44

which of the following drug is used for myoclonic sezure?

sodium valporate

MgSO4

BZ

Question 29

29/44

pharmacological effecs of BZ includes?

Question 30

30/44

which drug is used often for minor or absence seizure?

succineamide

phenytoin

Question 31

31/44

which of the following drug is benzodiazepine causes sedation?

diazepam

Question 32

32/44

benzodiazepine causes anti-anxiety at?

small dose

Question 33

33/44

for antiepileptisum which drug can be used?

phenobarbital

Question 34

34/44

patients with hepatic and renal failure can use?

paraldehyde

Question 35

35/44

the pharmacological effects of bensodiazepines include all of the following except?

Question 36

36/44

uses of amantadine?

Hint: 1 choice

Question 37

37/44

the pharmacological effects of barbiturates include?

Question 38

38/44

which of the following drug in BZ is used for muscle relaxation?

diazepam

Question 39

39/44

which of the following drug is used in BZ for terminating grand mal and status epilepsy?

diazepam

Question 40

40/44

uses of trihexayphendiyl?

Hint: 2 choices

Question 41

41/44

which of the following drugs are used for anti Anxeity?

BZ

MgSO4

Question 42

42/44

drug used in myoclonic seizure and absence in children?

chlonazepam

diazepam

Question 43

43/44

drug effective for all parsial seizurs?

diazepam

carbamizepam

Question 44

44/44

classification of parkinsonian disorders drugs are?

Hint: 6 choices