Pharmacology (2) Drugs Affecting central nervous system practice test [As you grow,the beauty steals inward] shema published on November 14, 201215 responses 0 « Previous Next » Questions in vertical order 1/44 which drug is used for absence epilepsy as a second choice? sodium valporate BZ MgSO4 2/44 characteristics of sleep induced by barbiturates is? to shorten SEMS to shorten REMS to prolong SEMS to prolong REMS to shorten REMS and SEMS 3/44 carbidopa? Hint: 4 choices inhibitor of dopa decarboxylase reduce peripheral conversion of L-dopa to dopamine uses: combination with L-dopa its not used alone can use alone 4/44 which of the following drug cause small reduction in REM sleep? chloralhydrate paraldehydrate phenobarbital 5/44 trihexayphenidyl? less efficious than levodopa more effictive in tremor less effective in bradykinesia and rigidity 6/44 uses of amantadine? Hint: 1 choice do not use alone for early parkinson's disease alone used for early parkinson's disease various parkinson's diseases: in combination with L-dopa 7/44 drug used in myoclonic seizure and absence in children? chlonazepam carbamizepam diazepam 8/44 which of following BARB are lowerly lipid soluble? long acting short acting ultra short acting 9/44 adverse effect of levodopa? Hint: 3 choices tachycardia,arrythmia vivid dream,mental disturbance,GIT(nausea vomiting) no vit B6 during therapy vit B6 during therapy 10/44 therapeutic uses of levodopa? Hint: 2 choices effective for parkinsonian disease and syndrome combination with L-dopa and carbidopa effective only for parkinsonian disease 11/44 benzodiazepine includes? chlordiazepoxide and diazepam thiopental and hlordiazepoxide L-dopa and carbidopa 12/44 BARB are being replaced by bensodiazepines (BZ) for clinical use as sedative hypnotic agents b/c of the following short comings ? a narrow therapeutic index, shortening REMS and hight potential for physical dependence induction of seizures and shortening REMS Induction of seizures and a narrow therapeutic index 13/44 which of the following drugs in BZ is used for hypnosis? flurazepam,temazepam,triazolam chloradiazepoxide and diazepam diazepam and flurazepam 14/44 drug effective for all parsial seizurs? diazepam carbamizepam chlonazepam 15/44 which of the following is the first choice for epileticism in adult? phenytoin phenobarbital oral diazepam magnesium sulfate injection all of the above 16/44 which of the following drugs are used as first choice in children's and infants? barbiturates BZ seccineamide 17/44 which of the following drug in BZ is used for muscle relaxation? diazepam chlonazepam flurazepam 18/44 intravenous anesthesia which drug is used? thiopeutal phenobarbital amobarbital 19/44 which of the following BARB are highly lipid soluble? ultra short acting barbiturates long acting short acting 20/44 which are true about pharmacokinetics of Leodopa? Hint: 2 choices doesnt cross BBB well absorbed from small intestine and 90% decarboxylated in periphral and results in peripheral side effect cross BBB 21/44 which of the following drug is benzodiazepine causes anti anxiety? Florazepam and temazepam chloradiazepoxide and diazepam chlorazepam and diazepam 22/44 patients with hepatic and renal failure can use? paraldehyde chloralhydrate phenobarbital 23/44 the pharmacological effects of bensodiazepines include all of the following except? antianxiety sedation hypnosis anticonvulsion anesthesia 24/44 amantadine? Hint: 3 choices stimulating synthesis and release of dopamine from surviving dopamine nerve terminals more effective than anti cholinergic agents not effective for tremors more effective than L-dopa in parkinson's disorder 25/44 for antiepileptisum which drug can be used? phenobarbital thiopental pentobarbital 26/44 which of the following drug is used in BZ for terminating grand mal and status epilepsy? diazepam chlonazepam flurazepam 27/44 benzodiazepine causes anti-anxiety at? sedative dose small dose large dose 28/44 the pharmacological effects of barbiturates include? sedation hypnosis anticonvulsion antiepileptism all of the above 29/44 drugs used in simple partial and grand mal epilepsy? BZ phenytoin succineamide barbiturates 30/44 which drug is used often for minor or absence seizure? succineamide barbiturate phenytoin 31/44 which of the following drug is used to treat grand mal epilepsy,partial epilepsy,anti peripheral neuralgia,antiarrhythmia? phenytoin barbiturate succineamide 32/44 which of the followings are true about parkinsonian disorders? Hint: 3 choices tremor,muscular rigdety,bradykinesia therapy: restablish dopamine/ Ach balance,to increase function of dopaminergic neurons in nuostratium,to decrease function of cholinergic neurons clinical effects: relieving symptoms, not stopping progress clinical effects: stopping progress 33/44 due to following shortcomings benzodiazepines replaces BARB except? a narrow therapeutic index shortening REMS induction of seizures hight potential for physical dependence 34/44 which of the following drug is benzodiazepine causes sedation? chlordiazepoxide diazepam flurazepam 35/44 adverse effects of amantadine? agitation and confusion restlessness hallucination 36/44 A patient suffering from toxication due to overdosage of barbiturates should be adminstered? intravenous infusion of NaHCO3 respiratory stimulant cardiovascular stimulant diuretics all of above 37/44 uses of trihexayphendiyl? Hint: 2 choices alone for mild patients: patients of discontinuation L-dopa due to adverse effects all parkinson's disorders: in combination with L-dopa not alone for mild patients: patients of discontinuation L-dopa due to adverse effects 38/44 which of the following drugs are used for anti Anxeity? BZ Barbiturates MgSO4 39/44 which of the following drug in BZ is used for chronic epilepsy? diazepam chlonazepam flurazepame 40/44 the clinical uses of phenytoin include all of the following except? grand mal seizure psychomotor seizure localizied seizure minor seizure 41/44 which of the following drug is used for myoclonic sezure? sodium valporate MgSO4 BZ 42/44 which of the following drugs are lipophilic and rapidly absorbed by oral administration? BZ barbiturates MgSO4 43/44 pharmacological effecs of BZ includes? sedation antianxiety hypnosis anticonvulsion all of the abvoe 44/44 classification of parkinsonian disorders drugs are? Hint: 6 choices dopaminomimetic) metabolite precursor:levodopa dopaminomimetic) decarboxylase inhibitor:carbidopa dopaminomimetic) DA receptor agonist: bromocriptine dopaminomimetic) MAO inhibitor: selegiline dopaminomimetic) COMT inhibitor: tocapone dopaminomimetic) drug releasing dopamine: amantadine anticholinergic drug: trihexyphenidy