Pathophysiology Practice Test (17) <<<<<<<<<<< Liver Insufficiency>>>>>>>>>>> ................. . Multiple Choice. ...................... shema published on June 21, 2012 Stacked 1/15 plasma amino acid imbalance may lead to? increased production of phenyl-ethanolamine increased of 5- HT increased production octopamine decreased production of dopamine 2/15 hyperammonemia in patient with cirrhosis related to? inadequate digestion of protein and excess reproduction of intestinal bacteria disorder of kidney alkalosis increased ammonia formation of the mucles 3/15 the patient with hepatic encephalopathy may have? Hint: 2 choices increased AAA ( aromatic amino acid) in plasma decreased GABA in plasma decreased BCAA ( branched chain amino acid) in plasma decreased phenylalanine in plasma 4/15 imbalance of plasma amino acid may lead to? Hint: 2 choices less AAA enter the brain more BCAA enter the brain decreased formation of dopamine increased formation of false neurotransmitter 5/15 the pathogenesis of hepatic ascites is? portal hypertension decreased plasma colloidal osmotic pressure decreased GFR excessive aldosterone 6/15 the pathogenesis of hepatic encephalopathy result from hyperammonemia are? Hint: 3 choices increased consume of ATP decrease production of ATP increased formation of false neurotransmitter increased formation of inhibited neurotransmitter 7/15 what may present in patients with hepatic insufficiency? encephalopathy hypoproteinemia hyperinsulinemia renal failure 8/15 the pathogenesis of disorder of energy metabolic in brain result from hyperammonemia are? Hint: 3 choices increased consume of α - ketoglutaric acid increased consume of NADH increased consume of ATP increased of acetyle-CoA 9/15 patients with hepatic cirrhosis may have? Hint: 3 choices increased ADH in the body increased ALD in the body increased phagocytic role of kupffer intestinal endotoxemia may occur cells 10/15 hepatic encephalopathy lead by false neurotransmitter is because? Hint: 2 choices FNT may compete with true neurotransmitter disturb production of energy FNT accumulated in the synapses of the reticular structure increase GABA 11/15 the proper treatment of hepatic encephalopathy is? L- dopa reduce oral intake of protein sterilizing the bowel with antibiotics such as neomycin acidification of the gut lumen by giving lactulose 12/15 the pathogenesis of hepatic encephalopathy by false neurotransmitter is? Hint: 2 choices easily enter blood-brain barrier there is specific receptor of FNT in membraine of neuron FNT may uptake and store and release by neuron FNT play weak physiological effects 13/15 precipitating causes of hepatic encephalopathy is? gastrointestinal hemorrhage alkalosis due to diuretic constipation infection 14/15 false neurotransmitter refers to? Hint: 2 choices phenyl-ethanolamine phenyl-ethylamine octopamine tyromine 15/15 precipitating factors of hepatic encephalopathy may be? prerenal azotemia sedative and anesthetic agents drink excessive alcohol operation